L462-0267 Screening compound: 2-{1,3-diethyl-2,4-dioxo-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidin-7-yl}-N-[(3,4,5-trimethoxyphenyl)methyl]acetamide

L462-0267 Screening compound: 2-{1,3-diethyl-2,4-dioxo-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidin-7-yl}-N-[(3,4,5-trimethoxyphenyl)methyl]acetamide
L462-0267 Screening compound: 2-{1,3-diethyl-2,4-dioxo-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidin-7-yl}-N-[(3,4,5-trimethoxyphenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L462-0267
2-{1,3-diethyl-2,4-dioxo-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidin-7-yl}-N-[(3,4,5-trimethoxyphenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L462-0267

Molecular Formula

C22H28N4O6 (C22 H28 N4 O6)

Compound Name

2-{1,3-diethyl-2,4-dioxo-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidin-7-yl}-N-[(3,4,5-trimethoxyphenyl)methyl]acetamide

IUPAC name

2-{13-diethyl-24-dioxo-1H2H3H4H7H-pyrrolo[23-d]pyrimidin-7-yl}-N-[(345-trimethoxyphenyl)methyl]acetamide

SMILES

CCN(c(n(CC(NCc(cc1OC)cc(OC)c1OC)=O)cc1)c1C(N1CC)=O)C1=O

InChI

InChI=1S/C22H28N4O6/c1-6-25-20-15(21(28)26(7-2)22(25)29)8-9-24(20)13-18(27)23-12-14-10-16(30-3)19(32-5)17(11-14)31-4/h8-11H,6-7,12-13H2,1-5H3,(H,23,27)

InChI Key

DTZQTRDJWGWCMN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254293

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.045

Distribution Coefficient, logD

2.045

Water Solubility, LogSw

-3.09

Polar Surface Area

81.051

Acid Dissociation Constant (pKa)

15.17

Base Dissociation Constant (pKb)

0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L462-0267 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with L462-0267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L462-0267?
Check Price and Availability of L462-0267, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L462-0267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L462-0267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L462-0267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L462-0267 available by request