L464-0452 Screening compound: 5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-fluorophenyl)thiophene-2-sulfonamide

L464-0452 Screening compound: 5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-fluorophenyl)thiophene-2-sulfonamide
L464-0452 Screening compound: 5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-fluorophenyl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L464-0452
5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-fluorophenyl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L464-0452

Molecular Formula

C15H13FN2O3S2 (C15 H13 FN2 O3 S2)

Compound Name

5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-fluorophenyl)thiophene-2-sulfonamide

IUPAC name

5-(34-dimethyl-12-oxazol-5-yl)-N-(4-fluorophenyl)thiophene-2-sulfonamide

SMILES

Cc1c(-c(s2)ccc2S(Nc(cc2)ccc2F)(=O)=O)onc1C

InChI

InChI=1S/C15H13FN2O3S2/c1-9-10(2)17-21-15(9)13-7-8-14(22-13)23(19,20)18-12-5-3-11(16)4-6-12/h3-8,18H,1-2H3

InChI Key

HCMCNYJSVVESLJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254514

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.102

Distribution Coefficient, logD

3.853

Water Solubility, LogSw

-4.16

Polar Surface Area

64.251

Acid Dissociation Constant (pKa)

7.51

Base Dissociation Constant (pKb)

-0.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

L464-0452 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L464-0452 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L464-0452?
Check Price and Availability of L464-0452, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L464-0452 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L464-0452
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L464-0452
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L464-0452 available by request