L464-0469 Screening compound: 3,4-dimethyl-5-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-1,2-oxazole

L464-0469 Screening compound: 3,4-dimethyl-5-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-1,2-oxazole
L464-0469 Screening compound: 3,4-dimethyl-5-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-1,2-oxazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L464-0469
3,4-dimethyl-5-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-1,2-oxazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L464-0469

Molecular Formula

C13H16N2O3S2 (C13 H16 N2 O3 S2)

Compound Name

3,4-dimethyl-5-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-1,2-oxazole

IUPAC name

34-dimethyl-5-[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]-12-oxazole

SMILES

Cc1c(-c(s2)ccc2S(N2CCCC2)(=O)=O)onc1C

InChI

InChI=1S/C13H16N2O3S2/c1-9-10(2)14-18-13(9)11-5-6-12(19-11)20(16,17)15-7-3-4-8-15/h5-6H,3-4,7-8H2,1-2H3

InChI Key

TWXFWUYDGHBCJX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254526

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

312.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.907

Distribution Coefficient, logD

2.907

Water Solubility, LogSw

-3.24

Polar Surface Area

55.679

Acid Dissociation Constant (pKa)

24.60

Base Dissociation Constant (pKb)

-0.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

L464-0469 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L464-0469 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L464-0469?
Check Price and Availability of L464-0469, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L464-0469 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L464-0469
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L464-0469
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L464-0469 available by request