L466-0082 Screening compound: 1-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-[4-(quinoxalin-2-yl)phenoxy]ethan-1-one

L466-0082 Screening compound: 1-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-[4-(quinoxalin-2-yl)phenoxy]ethan-1-one
L466-0082 Screening compound: 1-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-[4-(quinoxalin-2-yl)phenoxy]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L466-0082
1-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-[4-(quinoxalin-2-yl)phenoxy]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L466-0082

Molecular Formula

C28H28N4O2 (C28 H28 N4 O2)

Compound Name

1-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-[4-(quinoxalin-2-yl)phenoxy]ethan-1-one

IUPAC name

1-[4-(23-dimethylphenyl)piperazin-1-yl]-2-[4-(quinoxalin-2-yl)phenoxy]ethan-1-one

SMILES

Cc1cccc(N(CC2)CCN2C(COc(cc2)ccc2-c2nc3ccccc3nc2)=O)c1C

InChI

InChI=1S/C28H28N4O2/c1-20-6-5-9-27(21(20)2)31-14-16-32(17-15-31)28(33)19-34-23-12-10-22(11-13-23)26-18-29-24-7-3-4-8-25(24)30-26/h3-13,18H,14-17,19H2,1-2H3

InChI Key

VMVRLGFATXUXFS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254655

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.378

Distribution Coefficient, logD

5.378

Water Solubility, LogSw

-5.28

Polar Surface Area

44.001

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L466-0082 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L466-0082 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L466-0082?
Check Price and Availability of L466-0082, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L466-0082 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L466-0082
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L466-0082
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L466-0082 available by request