L466-0246 Screening compound: N-[(2-methylphenyl)methyl]-2-[4-(quinoxalin-2-yl)phenoxy]acetamide

L466-0246 Screening compound: N-[(2-methylphenyl)methyl]-2-[4-(quinoxalin-2-yl)phenoxy]acetamide
L466-0246 Screening compound: N-[(2-methylphenyl)methyl]-2-[4-(quinoxalin-2-yl)phenoxy]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L466-0246
N-[(2-methylphenyl)methyl]-2-[4-(quinoxalin-2-yl)phenoxy]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L466-0246

Molecular Formula

C24H21N3O2 (C24 H21 N3 O2)

Compound Name

N-[(2-methylphenyl)methyl]-2-[4-(quinoxalin-2-yl)phenoxy]acetamide

IUPAC name

N-[(2-methylphenyl)methyl]-2-[4-(quinoxalin-2-yl)phenoxy]acetamide

SMILES

Cc1c(CNC(COc(cc2)ccc2-c2nc3ccccc3nc2)=O)cccc1

InChI

InChI=1S/C24H21N3O2/c1-17-6-2-3-7-19(17)14-26-24(28)16-29-20-12-10-18(11-13-20)23-15-25-21-8-4-5-9-22(21)27-23/h2-13,15H,14,16H2,1H3,(H,26,28)

InChI Key

TXPZGJKQUZARJB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254714

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.203

Distribution Coefficient, logD

5.203

Water Solubility, LogSw

-4.95

Polar Surface Area

49.121

Acid Dissociation Constant (pKa)

12.45

Base Dissociation Constant (pKb)

2.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

L466-0246 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L466-0246 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L466-0246?
Check Price and Availability of L466-0246, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L466-0246 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L466-0246
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L466-0246
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L466-0246 available by request