L466-0495 Screening compound: N-(4-methylpyridin-2-yl)-2-[4-(quinoxalin-2-yl)phenoxy]propanamide

L466-0495 Screening compound: N-(4-methylpyridin-2-yl)-2-[4-(quinoxalin-2-yl)phenoxy]propanamide
L466-0495 Screening compound: N-(4-methylpyridin-2-yl)-2-[4-(quinoxalin-2-yl)phenoxy]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L466-0495
N-(4-methylpyridin-2-yl)-2-[4-(quinoxalin-2-yl)phenoxy]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L466-0495

Molecular Formula

C23H20N4O2 (C23 H20 N4 O2)

Compound Name

N-(4-methylpyridin-2-yl)-2-[4-(quinoxalin-2-yl)phenoxy]propanamide

IUPAC name

N-(4-methylpyridin-2-yl)-2-[4-(quinoxalin-2-yl)phenoxy]propanamide

SMILES

CC(C(Nc1nccc(C)c1)=O)Oc(cc1)ccc1-c1nc2ccccc2nc1

InChI

InChI=1S/C23H20N4O2/c1-15-11-12-24-22(13-15)27-23(28)16(2)29-18-9-7-17(8-10-18)21-14-25-19-5-3-4-6-20(19)26-21/h3-14,16H,1-2H3,(H,24,27,28)/t16-/m0/s1

InChI Key

UYEIKKVTSDGPHA-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27254769

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.637

Distribution Coefficient, logD

4.636

Water Solubility, LogSw

-4.27

Polar Surface Area

56.917

Acid Dissociation Constant (pKa)

10.69

Base Dissociation Constant (pKb)

2.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

L466-0495 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L466-0495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L466-0495?
Check Price and Availability of L466-0495, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L466-0495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L466-0495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L466-0495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L466-0495 available by request