L470-0100 Screening compound: 3-(1H-indol-3-yl)-N-{[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]methyl}propanamide

L470-0100 Screening compound: 3-(1H-indol-3-yl)-N-{[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]methyl}propanamide
L470-0100 Screening compound: 3-(1H-indol-3-yl)-N-{[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]methyl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-0100
3-(1H-indol-3-yl)-N-{[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]methyl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-0100

Molecular Formula

C20H23N3O3S2 (C20 H23 N3 O3 S2)

Compound Name

3-(1H-indol-3-yl)-N-{[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]methyl}propanamide

IUPAC name

3-(1H-indol-3-yl)-N-{[5-(pyrrolidine-1-sulfonyl)thiophen-2-yl]methyl}propanamide

SMILES

O=C(CCc1c[nH]c2c1cccc2)NCc(s1)ccc1S(N1CCCC1)(=O)=O

InChI

InChI=1S/C20H23N3O3S2/c24-19(9-7-15-13-21-18-6-2-1-5-17(15)18)22-14-16-8-10-20(27-16)28(25,26)23-11-3-4-12-23/h1-2,5-6,8,10,13,21H,3-4,7,9,11-12,14H2,(H,22,24)

InChI Key

CVMSOOMRZWGYLH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254867

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.186

Distribution Coefficient, logD

3.186

Water Solubility, LogSw

-3.34

Polar Surface Area

67.404

Acid Dissociation Constant (pKa)

13.41

Base Dissociation Constant (pKb)

-2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

L470-0100 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L470-0100 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-0100?
Check Price and Availability of L470-0100, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L470-0100 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-0100
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-0100
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-0100 available by request