L470-0678 Screening compound: N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-2-bromobenzamide

L470-0678 Screening compound: N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-2-bromobenzamide
L470-0678 Screening compound: N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-2-bromobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-0678
N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-2-bromobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-0678

Molecular Formula

C18H21BrN2O3S2 (C18 H21 BrN2 O3 S2)

Compound Name

N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-2-bromobenzamide

IUPAC name

N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-2-bromobenzamide

SMILES

O=C(c(cccc1)c1Br)NCc(s1)ccc1S(N1CCCCCC1)(=O)=O

InChI

InChI=1S/C18H21BrN2O3S2/c19-16-8-4-3-7-15(16)18(22)20-13-14-9-10-17(25-14)26(23,24)21-11-5-1-2-6-12-21/h3-4,7-10H,1-2,5-6,11-13H2,(H,20,22)

InChI Key

ZAXHISQCRNLRKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27255031

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.156

Distribution Coefficient, logD

4.156

Water Solubility, LogSw

-4.24

Polar Surface Area

57.712

Acid Dissociation Constant (pKa)

11.56

Base Dissociation Constant (pKb)

-3.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

L470-0678 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L470-0678 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-0678?
Check Price and Availability of L470-0678, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L470-0678 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-0678
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-0678
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-0678 available by request