L470-0740 Screening compound: N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-5-chloro-1H-indole-2-carboxamide

L470-0740 Screening compound: N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-5-chloro-1H-indole-2-carboxamide
L470-0740 Screening compound: N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-5-chloro-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-0740
N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-5-chloro-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-0740

Molecular Formula

C20H22ClN3O3S2 (C20 H22 ClN3 O3 S2)

Compound Name

N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-5-chloro-1H-indole-2-carboxamide

IUPAC name

N-{[5-(azepane-1-sulfonyl)thiophen-2-yl]methyl}-5-chloro-1H-indole-2-carboxamide

SMILES

O=C(c1cc(cc(cc2)Cl)c2[nH]1)NCc(s1)ccc1S(N1CCCCCC1)(=O)=O

InChI

InChI=1S/C20H22ClN3O3S2/c21-15-5-7-17-14(11-15)12-18(23-17)20(25)22-13-16-6-8-19(28-16)29(26,27)24-9-3-1-2-4-10-24/h5-8,11-12,23H,1-4,9-10,13H2,(H,22,25)

InChI Key

GRDGGOWFRWDZJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27255061

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.933

Distribution Coefficient, logD

4.933

Water Solubility, LogSw

-4.91

Polar Surface Area

67.061

Acid Dissociation Constant (pKa)

13.44

Base Dissociation Constant (pKb)

-3.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

L470-0740 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L470-0740 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-0740?
Check Price and Availability of L470-0740, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L470-0740 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-0740
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-0740
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-0740 available by request