L470-1137 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3,4-difluorobenzamide

L470-1137 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3,4-difluorobenzamide
L470-1137 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3,4-difluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-1137
N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3,4-difluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-1137

Molecular Formula

C14H14F2N2O3S2 (C14 H14 F2 N2 O3 S2)

Compound Name

N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3,4-difluorobenzamide

IUPAC name

N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-34-difluorobenzamide

SMILES

CN(C)S(c1ccc(CNC(c(cc2)cc(F)c2F)=O)s1)(=O)=O

InChI

InChI=1S/C14H14F2N2O3S2/c1-18(2)23(20,21)13-6-4-10(22-13)8-17-14(19)9-3-5-11(15)12(16)7-9/h3-7H,8H2,1-2H3,(H,17,19)

InChI Key

KAKWGEZLYRAAEQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27255074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.644

Distribution Coefficient, logD

2.644

Water Solubility, LogSw

-3.14

Polar Surface Area

59.334

Acid Dissociation Constant (pKa)

10.66

Base Dissociation Constant (pKb)

-3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

L470-1137 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L470-1137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-1137?
Check Price and Availability of L470-1137, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L470-1137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-1137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-1137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-1137 available by request