L470-1192 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3-(1H-indol-3-yl)propanamide

L470-1192 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3-(1H-indol-3-yl)propanamide
L470-1192 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3-(1H-indol-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-1192
N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3-(1H-indol-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-1192

Molecular Formula

C18H21N3O3S2 (C18 H21 N3 O3 S2)

Compound Name

N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3-(1H-indol-3-yl)propanamide

IUPAC name

N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-3-(1H-indol-3-yl)propanamide

SMILES

CN(C)S(c1ccc(CNC(CCc2c[nH]c3c2cccc3)=O)s1)(=O)=O

InChI

InChI=1S/C18H21N3O3S2/c1-21(2)26(23,24)18-10-8-14(25-18)12-20-17(22)9-7-13-11-19-16-6-4-3-5-15(13)16/h3-6,8,10-11,19H,7,9,12H2,1-2H3,(H,20,22)

InChI Key

OPLQUKZWADIIHN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD17853375

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.732

Distribution Coefficient, logD

2.732

Water Solubility, LogSw

-3.22

Polar Surface Area

68.991

Acid Dissociation Constant (pKa)

13.41

Base Dissociation Constant (pKb)

-3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

L470-1192 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Targets:
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L470-1192 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-1192?
Check Price and Availability of L470-1192, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L470-1192 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-1192
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-1192
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-1192 available by request