L470-1211 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-1-(4-methoxyphenyl)cyclopropane-1-carboxamide

L470-1211 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-1-(4-methoxyphenyl)cyclopropane-1-carboxamide
L470-1211 Screening compound: N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-1-(4-methoxyphenyl)cyclopropane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-1211
N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-1-(4-methoxyphenyl)cyclopropane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-1211

Molecular Formula

C18H22N2O4S2 (C18 H22 N2 O4 S2)

Compound Name

N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-1-(4-methoxyphenyl)cyclopropane-1-carboxamide

IUPAC name

N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}-1-(4-methoxyphenyl)cyclopropane-1-carboxamide

SMILES

CN(C)S(c1ccc(CNC(C2(CC2)c(cc2)ccc2OC)=O)s1)(=O)=O

InChI

InChI=1S/C18H22N2O4S2/c1-20(2)26(22,23)16-9-8-15(25-16)12-19-17(21)18(10-11-18)13-4-6-14(24-3)7-5-13/h4-9H,10-12H2,1-3H3,(H,19,21)

InChI Key

KBJMOMVWQRMHHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27255087

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.677

Distribution Coefficient, logD

2.677

Water Solubility, LogSw

-3.07

Polar Surface Area

67.129

Acid Dissociation Constant (pKa)

13.14

Base Dissociation Constant (pKb)

-1.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

L470-1211 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Others

References: we are preparing a list of scientific research reports with L470-1211 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-1211?
Check Price and Availability of L470-1211, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L470-1211 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-1211
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-1211
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-1211 available by request