L470-1214 Screening compound: 2-(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}acetamide

L470-1214 Screening compound: 2-(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}acetamide
L470-1214 Screening compound: 2-(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L470-1214
2-(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L470-1214

Molecular Formula

C17H18ClN3O5S2 (C17 H18 ClN3 O5 S2)

Compound Name

2-(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}acetamide

IUPAC name

2-(6-chloro-3-oxo-34-dihydro-2H-14-benzoxazin-4-yl)-N-{[5-(dimethylsulfamoyl)thiophen-2-yl]methyl}acetamide

SMILES

CN(C)S(c1ccc(CNC(CN2c(cc(cc3)Cl)c3OCC2=O)=O)s1)(=O)=O

InChI

InChI=1S/C17H18ClN3O5S2/c1-20(2)28(24,25)17-6-4-12(27-17)8-19-15(22)9-21-13-7-11(18)3-5-14(13)26-10-16(21)23/h3-7H,8-10H2,1-2H3,(H,19,22)

InChI Key

SCKXSFZXDJPUCE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27255089

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.93

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.902

Distribution Coefficient, logD

1.902

Water Solubility, LogSw

-3.02

Polar Surface Area

83.222

Acid Dissociation Constant (pKa)

13.80

Base Dissociation Constant (pKb)

-2.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L470-1214 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L470-1214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L470-1214?
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What is the minimum amount of L470-1214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L470-1214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L470-1214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L470-1214 available by request