L472-1246 Screening compound: 4-chloro-N-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)benzene-1-sulfonamide

L472-1246 Screening compound: 4-chloro-N-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)benzene-1-sulfonamide
L472-1246 Screening compound: 4-chloro-N-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L472-1246
4-chloro-N-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L472-1246

Molecular Formula

C21H17ClN4O3S2 (C21 H17 ClN4 O3 S2)

Compound Name

4-chloro-N-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)benzene-1-sulfonamide

IUPAC name

4-chloro-N-({3-[4-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-124-oxadiazol-5-yl}methyl)benzene-1-sulfonamide

SMILES

O=S(c(cc1)ccc1Cl)(NCc1nc(-c(cc2)ccc2-c2csc(C3CC3)n2)no1)=O

InChI

InChI=1S/C21H17ClN4O3S2/c22-16-7-9-17(10-8-16)31(27,28)23-11-19-25-20(26-29-19)14-3-1-13(2-4-14)18-12-30-21(24-18)15-5-6-15/h1-4,7-10,12,15,23H,5-6,11H2

InChI Key

UOVJHWYQGQZKSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27455052

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.98

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.816

Distribution Coefficient, logD

5.744

Water Solubility, LogSw

-6.34

Polar Surface Area

83.325

Acid Dissociation Constant (pKa)

8.14

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

L472-1246 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L472-1246 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L472-1246?
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What is the minimum amount of L472-1246 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L472-1246
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L472-1246
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L472-1246 available by request