L472-1254 Screening compound: N-(3-{3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-2-methylphenyl)acetamide

L472-1254 Screening compound: N-(3-{3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-2-methylphenyl)acetamide
L472-1254 Screening compound: N-(3-{3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-2-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L472-1254
N-(3-{3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-2-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L472-1254

Molecular Formula

C23H20N4O2S (C23 H20 N4 O2 S)

Compound Name

N-(3-{3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}-2-methylphenyl)acetamide

IUPAC name

N-(3-{3-[4-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-124-oxadiazol-5-yl}-2-methylphenyl)acetamide

SMILES

CC(Nc1cccc(-c2nc(-c(cc3)ccc3-c3csc(C4CC4)n3)no2)c1C)=O

InChI

InChI=1S/C23H20N4O2S/c1-13-18(4-3-5-19(13)24-14(2)28)22-26-21(27-29-22)16-8-6-15(7-9-16)20-12-30-23(25-20)17-10-11-17/h3-9,12,17H,10-11H2,1-2H3,(H,24,28)

InChI Key

UQVMBXHGLDWYNP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27455055

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.106

Distribution Coefficient, logD

5.106

Water Solubility, LogSw

-4.85

Polar Surface Area

64.194

Acid Dissociation Constant (pKa)

13.31

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L472-1254 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L472-1254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L472-1254?
Check Price and Availability of L472-1254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L472-1254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L472-1254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L472-1254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L472-1254 available by request