L472-1259 Screening compound: 3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazole

L472-1259 Screening compound: 3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazole
L472-1259 Screening compound: 3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L472-1259
3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L472-1259

Molecular Formula

C19H16N4OS2 (C19 H16 N4 OS2)

Compound Name

3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazole

IUPAC name

3-[4-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-5-(24-dimethyl-13-thiazol-5-yl)-124-oxadiazole

SMILES

Cc1c(-c2nc(-c(cc3)ccc3-c3csc(C4CC4)n3)no2)sc(C)n1

InChI

InChI=1S/C19H16N4OS2/c1-10-16(26-11(2)20-10)18-22-17(23-24-18)13-5-3-12(4-6-13)15-9-25-19(21-15)14-7-8-14/h3-6,9,14H,7-8H2,1-2H3

InChI Key

RTOOKFUSHKWODF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27455058

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.652

Distribution Coefficient, logD

5.652

Water Solubility, LogSw

-5.59

Polar Surface Area

52.019

Acid Dissociation Constant (pKa)

23.73

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

L472-1259 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L472-1259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L472-1259?
Check Price and Availability of L472-1259, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L472-1259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L472-1259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L472-1259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L472-1259 available by request