L472-1272 Screening compound: 1-(3-CHLOROPHENYL)-4-{3-[4-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-2-PYRROLIDINONE

L472-1272 Screening compound: 1-(3-CHLOROPHENYL)-4-{3-[4-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-2-PYRROLIDINONE
L472-1272 Screening compound: 1-(3-CHLOROPHENYL)-4-{3-[4-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-2-PYRROLIDINONE alternative view

Chemical Structure Depiction of ChemDiv screening compound L472-1272
1-(3-CHLOROPHENYL)-4-{3-[4-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-2-PYRROLIDINONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L472-1272

Molecular Formula

C24H19ClN4O2S (C24 H19 ClN4 O2 S)

Compound Name

1-(3-CHLOROPHENYL)-4-{3-[4-(2-CYCLOPROPYL-1,3-THIAZOL-4-YL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-2-PYRROLIDINONE

IUPAC name

1-(3-chlorophenyl)-4-{3-[4-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-124-oxadiazol-5-yl}pyrrolidin-2-one

SMILES

O=C(CC(C1)c2nc(-c(cc3)ccc3-c3csc(C4CC4)n3)no2)N1c1cccc(Cl)c1

InChI

InChI=1S/C24H19ClN4O2S/c25-18-2-1-3-19(11-18)29-12-17(10-21(29)30)23-27-22(28-31-23)15-6-4-14(5-7-15)20-13-32-24(26-20)16-8-9-16/h1-7,11,13,16-17H,8-10,12H2/t17-/m1/s1

InChI Key

OSHWYNDBRQWWCN-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD27455065

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.96

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.314

Distribution Coefficient, logD

6.314

Water Solubility, LogSw

-6.39

Polar Surface Area

58.380

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

L472-1272 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L472-1272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L472-1272?
Check Price and Availability of L472-1272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L472-1272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L472-1272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L472-1272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L472-1272 available by request