L472-1343 Screening compound: 3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[(2-fluorophenyl)methyl]-1,2,4-oxadiazole

L472-1343 Screening compound: 3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[(2-fluorophenyl)methyl]-1,2,4-oxadiazole
L472-1343 Screening compound: 3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[(2-fluorophenyl)methyl]-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L472-1343
3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[(2-fluorophenyl)methyl]-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L472-1343

Molecular Formula

C21H16FN3OS (C21 H16 FN3 OS)

Compound Name

3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-5-[(2-fluorophenyl)methyl]-1,2,4-oxadiazole

IUPAC name

3-[4-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-5-[(2-fluorophenyl)methyl]-124-oxadiazole

SMILES

Fc1c(Cc2nc(-c(cc3)ccc3-c3csc(C4CC4)n3)no2)cccc1

InChI

InChI=1S/C21H16FN3OS/c22-17-4-2-1-3-16(17)11-19-24-20(25-26-19)14-7-5-13(6-8-14)18-12-27-21(23-18)15-9-10-15/h1-8,12,15H,9-11H2

InChI Key

SESZJILCGXRFLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27455102

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.268

Distribution Coefficient, logD

6.268

Water Solubility, LogSw

-6.24

Polar Surface Area

41.295

Acid Dissociation Constant (pKa)

23.73

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

L472-1343 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L472-1343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L472-1343?
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What is the minimum amount of L472-1343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L472-1343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L472-1343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L472-1343 available by request