L472-1367 Screening compound: 6-chloro-4-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one

L472-1367 Screening compound: 6-chloro-4-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one
L472-1367 Screening compound: 6-chloro-4-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L472-1367
6-chloro-4-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L472-1367

Molecular Formula

C23H17ClN4O3S (C23 H17 ClN4 O3 S)

Compound Name

6-chloro-4-({3-[4-(2-cyclopropyl-1,3-thiazol-4-yl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one

IUPAC name

6-chloro-4-({3-[4-(2-cyclopropyl-13-thiazol-4-yl)phenyl]-124-oxadiazol-5-yl}methyl)-34-dihydro-2H-14-benzoxazin-3-one

SMILES

O=C1N(Cc2nc(-c(cc3)ccc3-c3csc(C4CC4)n3)no2)c(cc(cc2)Cl)c2OC1

InChI

InChI=1S/C23H17ClN4O3S/c24-16-7-8-19-18(9-16)28(21(29)11-30-19)10-20-26-22(27-31-20)14-3-1-13(2-4-14)17-12-32-23(25-17)15-5-6-15/h1-4,7-9,12,15H,5-6,10-11H2

InChI Key

DCEMOWJYOCEDPY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27455111

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.93

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.449

Distribution Coefficient, logD

5.449

Water Solubility, LogSw

-6.03

Polar Surface Area

65.397

Acid Dissociation Constant (pKa)

20.11

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L472-1367 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L472-1367 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L472-1367?
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What is the minimum amount of L472-1367 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L472-1367
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L472-1367
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L472-1367 available by request