L474-1728 Screening compound: N-(3-fluoro-4-methylphenyl)-2-[1-(pyrrolidine-1-carbonyl)-2,3-dihydro-1H-indole-5-sulfonamido]propanamide

L474-1728 Screening compound: N-(3-fluoro-4-methylphenyl)-2-[1-(pyrrolidine-1-carbonyl)-2,3-dihydro-1H-indole-5-sulfonamido]propanamide
L474-1728 Screening compound: N-(3-fluoro-4-methylphenyl)-2-[1-(pyrrolidine-1-carbonyl)-2,3-dihydro-1H-indole-5-sulfonamido]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L474-1728
N-(3-fluoro-4-methylphenyl)-2-[1-(pyrrolidine-1-carbonyl)-2,3-dihydro-1H-indole-5-sulfonamido]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L474-1728

Molecular Formula

C23H27FN4O4S (C23 H27 FN4 O4 S)

Compound Name

N-(3-fluoro-4-methylphenyl)-2-[1-(pyrrolidine-1-carbonyl)-2,3-dihydro-1H-indole-5-sulfonamido]propanamide

IUPAC name

N-(3-fluoro-4-methylphenyl)-2-[1-(pyrrolidine-1-carbonyl)-23-dihydro-1H-indole-5-sulfonamido]propanamide

SMILES

CC(C(Nc1cc(F)c(C)cc1)=O)NS(c(cc1)cc(CC2)c1N2C(N1CCCC1)=O)(=O)=O

InChI

InChI=1S/C23H27FN4O4S/c1-15-5-6-18(14-20(15)24)25-22(29)16(2)26-33(31,32)19-7-8-21-17(13-19)9-12-28(21)23(30)27-10-3-4-11-27/h5-8,13-14,16,26H,3-4,9-12H2,1-2H3,(H,25,29)/t16-/m0/s1

InChI Key

JEDTXCPQTVVFHX-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15128175

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.744

Distribution Coefficient, logD

3.742

Water Solubility, LogSw

-3.99

Polar Surface Area

82.587

Acid Dissociation Constant (pKa)

9.77

Base Dissociation Constant (pKb)

-0.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

L474-1728 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L474-1728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L474-1728?
Check Price and Availability of L474-1728, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L474-1728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L474-1728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L474-1728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L474-1728 available by request