L475-0081 Screening compound: 6-{[4-(4-chlorobenzoyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one

L475-0081 Screening compound: 6-{[4-(4-chlorobenzoyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one
L475-0081 Screening compound: 6-{[4-(4-chlorobenzoyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L475-0081
6-{[4-(4-chlorobenzoyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L475-0081

Molecular Formula

C18H16ClN3O4S2 (C18 H16 ClN3 O4 S2)

Compound Name

6-{[4-(4-chlorobenzoyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one

IUPAC name

6-{[4-(4-chlorobenzoyl)piperazin-1-yl]sulfonyl}-23-dihydro-13-benzothiazol-2-one

SMILES

O=C(c(cc1)ccc1Cl)N(CC1)CCN1S(c(cc1)cc(S2)c1NC2=O)(=O)=O

InChI

InChI=1S/C18H16ClN3O4S2/c19-13-3-1-12(2-4-13)17(23)21-7-9-22(10-8-21)28(25,26)14-5-6-15-16(11-14)27-18(24)20-15/h1-6,11H,7-10H2,(H,20,24)

InChI Key

OVTQCCIJXYEQDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27455188

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.93

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.890

Distribution Coefficient, logD

2.868

Water Solubility, LogSw

-3.71

Polar Surface Area

72.553

Acid Dissociation Constant (pKa)

8.69

Base Dissociation Constant (pKb)

-3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L475-0081 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L475-0081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L475-0081?
Check Price and Availability of L475-0081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L475-0081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L475-0081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L475-0081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L475-0081 available by request