L482-1003 Screening compound: N-[4-(carbamoylmethoxy)-2-(4-methoxyphenyl)quinolin-6-yl]-4-fluorobenzamide

L482-1003 Screening compound: N-[4-(carbamoylmethoxy)-2-(4-methoxyphenyl)quinolin-6-yl]-4-fluorobenzamide
L482-1003 Screening compound: N-[4-(carbamoylmethoxy)-2-(4-methoxyphenyl)quinolin-6-yl]-4-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L482-1003
N-[4-(carbamoylmethoxy)-2-(4-methoxyphenyl)quinolin-6-yl]-4-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L482-1003

Molecular Formula

C25H20FN3O4 (C25 H20 FN3 O4)

Compound Name

N-[4-(carbamoylmethoxy)-2-(4-methoxyphenyl)quinolin-6-yl]-4-fluorobenzamide

IUPAC name

N-[4-(carbamoylmethoxy)-2-(4-methoxyphenyl)quinolin-6-yl]-4-fluorobenzamide

SMILES

COc(cc1)ccc1-c1cc(OCC(N)=O)c(cc(cc2)NC(c(cc3)ccc3F)=O)c2n1

InChI

InChI=1S/C25H20FN3O4/c1-32-19-9-4-15(5-10-19)22-13-23(33-14-24(27)30)20-12-18(8-11-21(20)29-22)28-25(31)16-2-6-17(26)7-3-16/h2-13H,14H2,1H3,(H2,27,30)(H,28,31)

InChI Key

HNKKORIEQYDHSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456147

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.123

Distribution Coefficient, logD

4.119

Water Solubility, LogSw

-4.48

Polar Surface Area

79.906

Acid Dissociation Constant (pKa)

9.51

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

L482-1003 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with L482-1003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L482-1003?
Check Price and Availability of L482-1003, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L482-1003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L482-1003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L482-1003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L482-1003 available by request