L482-1441 Screening compound: N-[4-ethoxy-2-(4-fluorophenyl)quinolin-6-yl]furan-2-carboxamide

L482-1441 Screening compound: N-[4-ethoxy-2-(4-fluorophenyl)quinolin-6-yl]furan-2-carboxamide
L482-1441 Screening compound: N-[4-ethoxy-2-(4-fluorophenyl)quinolin-6-yl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L482-1441
N-[4-ethoxy-2-(4-fluorophenyl)quinolin-6-yl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L482-1441

Molecular Formula

C22H17FN2O3 (C22 H17 FN2 O3)

Compound Name

N-[4-ethoxy-2-(4-fluorophenyl)quinolin-6-yl]furan-2-carboxamide

IUPAC name

N-[4-ethoxy-2-(4-fluorophenyl)quinolin-6-yl]furan-2-carboxamide

SMILES

CCOc(c1c2)cc(-c(cc3)ccc3F)nc1ccc2NC(c1ccco1)=O

InChI

InChI=1S/C22H17FN2O3/c1-2-27-21-13-19(14-5-7-15(23)8-6-14)25-18-10-9-16(12-17(18)21)24-22(26)20-4-3-11-28-20/h3-13H,2H2,1H3,(H,24,26)

InChI Key

VOHWDLINPMFAMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456222

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.173

Distribution Coefficient, logD

5.173

Water Solubility, LogSw

-5.13

Polar Surface Area

47.177

Acid Dissociation Constant (pKa)

10.90

Base Dissociation Constant (pKb)

3.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

L482-1441 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L482-1441 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L482-1441?
Check Price and Availability of L482-1441, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L482-1441 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L482-1441
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L482-1441
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L482-1441 available by request