L482-1563 Screening compound: N-[4-(carbamoylmethoxy)-2-(4-methylphenyl)quinolin-6-yl]-2-(4-fluorophenoxy)acetamide

L482-1563 Screening compound: N-[4-(carbamoylmethoxy)-2-(4-methylphenyl)quinolin-6-yl]-2-(4-fluorophenoxy)acetamide
L482-1563 Screening compound: N-[4-(carbamoylmethoxy)-2-(4-methylphenyl)quinolin-6-yl]-2-(4-fluorophenoxy)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L482-1563
N-[4-(carbamoylmethoxy)-2-(4-methylphenyl)quinolin-6-yl]-2-(4-fluorophenoxy)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L482-1563

Molecular Formula

C26H22FN3O4 (C26 H22 FN3 O4)

Compound Name

N-[4-(carbamoylmethoxy)-2-(4-methylphenyl)quinolin-6-yl]-2-(4-fluorophenoxy)acetamide

IUPAC name

N-[4-(carbamoylmethoxy)-2-(4-methylphenyl)quinolin-6-yl]-2-(4-fluorophenoxy)acetamide

SMILES

Cc(cc1)ccc1-c1cc(OCC(N)=O)c(cc(cc2)NC(COc(cc3)ccc3F)=O)c2n1

InChI

InChI=1S/C26H22FN3O4/c1-16-2-4-17(5-3-16)23-13-24(34-14-25(28)31)21-12-19(8-11-22(21)30-23)29-26(32)15-33-20-9-6-18(27)7-10-20/h2-13H,14-15H2,1H3,(H2,28,31)(H,29,32)

InChI Key

AWEZGONOKWLPJW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456228

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.598

Distribution Coefficient, logD

4.597

Water Solubility, LogSw

-4.47

Polar Surface Area

79.648

Acid Dissociation Constant (pKa)

11.90

Base Dissociation Constant (pKb)

4.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

L482-1563 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L482-1563 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L482-1563?
Check Price and Availability of L482-1563, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L482-1563 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L482-1563
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L482-1563
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L482-1563 available by request