L482-1791 Screening compound: ethyl 2-{[6-(2H-1,3-benzodioxole-5-amido)-2-(4-fluorophenyl)quinolin-4-yl]oxy}acetate

L482-1791 Screening compound: ethyl 2-{[6-(2H-1,3-benzodioxole-5-amido)-2-(4-fluorophenyl)quinolin-4-yl]oxy}acetate
L482-1791 Screening compound: ethyl 2-{[6-(2H-1,3-benzodioxole-5-amido)-2-(4-fluorophenyl)quinolin-4-yl]oxy}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L482-1791
ethyl 2-{[6-(2H-1,3-benzodioxole-5-amido)-2-(4-fluorophenyl)quinolin-4-yl]oxy}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L482-1791

Molecular Formula

C27H21FN2O6 (C27 H21 FN2 O6)

Compound Name

ethyl 2-{[6-(2H-1,3-benzodioxole-5-amido)-2-(4-fluorophenyl)quinolin-4-yl]oxy}acetate

IUPAC name

ethyl 2-{[6-(2H-13-benzodioxole-5-amido)-2-(4-fluorophenyl)quinolin-4-yl]oxy}acetate

SMILES

CCOC(COc(c1c2)cc(-c(cc3)ccc3F)nc1ccc2NC(c(cc1)cc2c1OCO2)=O)=O

InChI

InChI=1S/C27H21FN2O6/c1-2-33-26(31)14-34-24-13-22(16-3-6-18(28)7-4-16)30-21-9-8-19(12-20(21)24)29-27(32)17-5-10-23-25(11-17)36-15-35-23/h3-13H,2,14-15H2,1H3,(H,29,32)

InChI Key

JGXNYGIDDHVORQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456260

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.319

Distribution Coefficient, logD

5.319

Water Solubility, LogSw

-5.53

Polar Surface Area

76.249

Acid Dissociation Constant (pKa)

11.36

Base Dissociation Constant (pKb)

3.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L482-1791 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L482-1791 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L482-1791?
Check Price and Availability of L482-1791, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L482-1791 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L482-1791
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L482-1791
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L482-1791 available by request