L482-1877 Screening compound: ethyl 2-({6-[2-(4-fluorophenoxy)acetamido]-2-phenylquinolin-4-yl}oxy)acetate

L482-1877 Screening compound: ethyl 2-({6-[2-(4-fluorophenoxy)acetamido]-2-phenylquinolin-4-yl}oxy)acetate
L482-1877 Screening compound: ethyl 2-({6-[2-(4-fluorophenoxy)acetamido]-2-phenylquinolin-4-yl}oxy)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L482-1877
ethyl 2-({6-[2-(4-fluorophenoxy)acetamido]-2-phenylquinolin-4-yl}oxy)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L482-1877

Molecular Formula

C27H23FN2O5 (C27 H23 FN2 O5)

Compound Name

ethyl 2-({6-[2-(4-fluorophenoxy)acetamido]-2-phenylquinolin-4-yl}oxy)acetate

IUPAC name

ethyl 2-({6-[2-(4-fluorophenoxy)acetamido]-2-phenylquinolin-4-yl}oxy)acetate

SMILES

CCOC(COc1c(cc(cc2)NC(COc(cc3)ccc3F)=O)c2nc(-c2ccccc2)c1)=O

InChI

InChI=1S/C27H23FN2O5/c1-2-33-27(32)17-35-25-15-24(18-6-4-3-5-7-18)30-23-13-10-20(14-22(23)25)29-26(31)16-34-21-11-8-19(28)9-12-21/h3-15H,2,16-17H2,1H3,(H,29,31)

InChI Key

YOBVNVWHGMCVBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456273

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.326

Distribution Coefficient, logD

5.326

Water Solubility, LogSw

-5.43

Polar Surface Area

66.419

Acid Dissociation Constant (pKa)

11.90

Base Dissociation Constant (pKb)

3.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L482-1877 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L482-1877 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L482-1877?
Check Price and Availability of L482-1877, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L482-1877 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L482-1877
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L482-1877
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L482-1877 available by request