L483-0391 Screening compound: 4-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}piperidin-1-yl)-6-fluoroquinoline-3-carbonitrile

L483-0391 Screening compound: 4-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}piperidin-1-yl)-6-fluoroquinoline-3-carbonitrile
L483-0391 Screening compound: 4-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}piperidin-1-yl)-6-fluoroquinoline-3-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound L483-0391
4-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}piperidin-1-yl)-6-fluoroquinoline-3-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L483-0391

Molecular Formula

C23H25FN4O3 (C23 H25 FN4 O3)

Compound Name

4-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}piperidin-1-yl)-6-fluoroquinoline-3-carbonitrile

IUPAC name

4-(4-{14-dioxa-8-azaspiro[4.5]decane-8-carbonyl}piperidin-1-yl)-6-fluoroquinoline-3-carbonitrile

SMILES

N#Cc1cnc(ccc(F)c2)c2c1N(CC1)CCC1C(N(CC1)CCC11OCCO1)=O

InChI

InChI=1S/C23H25FN4O3/c24-18-1-2-20-19(13-18)21(17(14-25)15-26-20)27-7-3-16(4-8-27)22(29)28-9-5-23(6-10-28)30-11-12-31-23/h1-2,13,15-16H,3-12H2

InChI Key

PCHKJKBFVDHTPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD16639014

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.215

Distribution Coefficient, logD

2.215

Water Solubility, LogSw

-2.67

Polar Surface Area

60.083

Acid Dissociation Constant (pKa)

22.83

Base Dissociation Constant (pKb)

4.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

L483-0391 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L483-0391 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L483-0391?
Check Price and Availability of L483-0391, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L483-0391 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L483-0391
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L483-0391
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L483-0391 available by request