L485-2372 Screening compound: ethyl 3-{[6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate

L485-2372 Screening compound: ethyl 3-{[6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate
L485-2372 Screening compound: ethyl 3-{[6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L485-2372
ethyl 3-{[6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L485-2372

Molecular Formula

C26H29N3O3 (C26 H29 N3 O3)

Compound Name

ethyl 3-{[6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate

IUPAC name

ethyl 3-{[6-methyl-2-(4-methylpiperidine-1-carbonyl)quinolin-4-yl]amino}benzoate

SMILES

CCOC(c1cc(Nc2cc(C(N3CCC(C)CC3)=O)nc3ccc(C)cc23)ccc1)=O

InChI

InChI=1S/C26H29N3O3/c1-4-32-26(31)19-6-5-7-20(15-19)27-23-16-24(25(30)29-12-10-17(2)11-13-29)28-22-9-8-18(3)14-21(22)23/h5-9,14-17H,4,10-13H2,1-3H3,(H,27,28)

InChI Key

XNBRFLDZBSBNLJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456774

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.556

Distribution Coefficient, logD

6.556

Water Solubility, LogSw

-5.68

Polar Surface Area

54.186

Acid Dissociation Constant (pKa)

19.02

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

L485-2372 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L485-2372 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L485-2372?
Check Price and Availability of L485-2372, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L485-2372 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L485-2372
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L485-2372
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L485-2372 available by request