L486-0361 Screening compound: 7-fluoro-3-[1-(methylsulfonyl)-4-piperidyl]-4(3H)-quinazolinone

L486-0361 Screening compound: 7-fluoro-3-[1-(methylsulfonyl)-4-piperidyl]-4(3H)-quinazolinone
L486-0361 Screening compound: 7-fluoro-3-[1-(methylsulfonyl)-4-piperidyl]-4(3H)-quinazolinone alternative view

Chemical Structure Depiction of ChemDiv screening compound L486-0361
7-fluoro-3-[1-(methylsulfonyl)-4-piperidyl]-4(3H)-quinazolinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L486-0361

Molecular Formula

C14H16FN3O3S (C14 H16 FN3 O3 S)

Compound Name

7-fluoro-3-[1-(methylsulfonyl)-4-piperidyl]-4(3H)-quinazolinone

IUPAC name

7-fluoro-3-(1-methanesulfonylpiperidin-4-yl)-34-dihydroquinazolin-4-one

SMILES

CS(N(CC1)CCC1N(C=Nc1c2ccc(F)c1)C2=O)(=O)=O

InChI

InChI=1S/C14H16FN3O3S/c1-22(20,21)17-6-4-11(5-7-17)18-9-16-13-8-10(15)2-3-12(13)14(18)19/h2-3,8-9,11H,4-7H2,1H3

InChI Key

RYTFZBGFPHJIJI-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.36

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.823

Distribution Coefficient, logD

0.823

Water Solubility, LogSw

-2.38

Polar Surface Area

57.009

Acid Dissociation Constant (pKa)

24.48

Base Dissociation Constant (pKb)

1.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.86

L486-0361 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L486-0361 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L486-0361?
Check Price and Availability of L486-0361, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L486-0361 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L486-0361
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L486-0361
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L486-0361 available by request