L486-0363 Screening compound: 3-[1-(benzylsulfonyl)-4-piperidyl]-7-fluoro-4(3H)-quinazolinone

L486-0363 Screening compound: 3-[1-(benzylsulfonyl)-4-piperidyl]-7-fluoro-4(3H)-quinazolinone
L486-0363 Screening compound: 3-[1-(benzylsulfonyl)-4-piperidyl]-7-fluoro-4(3H)-quinazolinone alternative view

Chemical Structure Depiction of ChemDiv screening compound L486-0363
3-[1-(benzylsulfonyl)-4-piperidyl]-7-fluoro-4(3H)-quinazolinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L486-0363

Molecular Formula

C20H20FN3O3S (C20 H20 FN3 O3 S)

Compound Name

3-[1-(benzylsulfonyl)-4-piperidyl]-7-fluoro-4(3H)-quinazolinone

IUPAC name

n/a

SMILES

O=C1N(C(CC2)CCN2S(Cc2ccccc2)(=O)=O)C=Nc2c1ccc(F)c2

InChI

InChI=1S/C20H20FN3O3S/c21-16-6-7-18-19(12-16)22-14-24(20(18)25)17-8-10-23(11-9-17)28(26,27)13-15-4-2-1-3-5-15/h1-7,12,14,17H,8-11,13H2

InChI Key

HPDGIPSEDDUMHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457061

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.107

Distribution Coefficient, logD

2.107

Water Solubility, LogSw

-3.04

Polar Surface Area

57.139

Acid Dissociation Constant (pKa)

20.60

Base Dissociation Constant (pKb)

1.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

L486-0363 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L486-0363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L486-0363?
Check Price and Availability of L486-0363, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L486-0363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L486-0363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L486-0363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L486-0363 available by request