L486-0388 Screening compound: 7-fluoro-3-{1-[3-(trifluoromethyl)benzenesulfonyl]piperidin-4-yl}-3,4-dihydroquinazolin-4-one

L486-0388 Screening compound: 7-fluoro-3-{1-[3-(trifluoromethyl)benzenesulfonyl]piperidin-4-yl}-3,4-dihydroquinazolin-4-one
L486-0388 Screening compound: 7-fluoro-3-{1-[3-(trifluoromethyl)benzenesulfonyl]piperidin-4-yl}-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L486-0388
7-fluoro-3-{1-[3-(trifluoromethyl)benzenesulfonyl]piperidin-4-yl}-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L486-0388

Molecular Formula

C20H17F4N3O3S (C20 H17 F4 N3 O3 S)

Compound Name

7-fluoro-3-{1-[3-(trifluoromethyl)benzenesulfonyl]piperidin-4-yl}-3,4-dihydroquinazolin-4-one

IUPAC name

7-fluoro-3-{1-[3-(trifluoromethyl)benzenesulfonyl]piperidin-4-yl}-34-dihydroquinazolin-4-one

SMILES

O=C1N(C(CC2)CCN2S(c2cc(C(F)(F)F)ccc2)(=O)=O)C=Nc2c1ccc(F)c2

InChI

InChI=1S/C20H17F4N3O3S/c21-14-4-5-17-18(11-14)25-12-27(19(17)28)15-6-8-26(9-7-15)31(29,30)16-3-1-2-13(10-16)20(22,23)24/h1-5,10-12,15H,6-9H2

InChI Key

TZPJKYFBXOIRHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128320

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.331

Distribution Coefficient, logD

3.331

Water Solubility, LogSw

-3.84

Polar Surface Area

57.245

Acid Dissociation Constant (pKa)

27.88

Base Dissociation Constant (pKb)

1.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

References: we are preparing a list of scientific research reports with L486-0388 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L486-0388?
Check Price and Availability of L486-0388, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L486-0388 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L486-0388
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L486-0388
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L486-0388 available by request