L486-0405 Screening compound: N-(3-methoxyphenyl)-4-(4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide

L486-0405 Screening compound: N-(3-methoxyphenyl)-4-(4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide
L486-0405 Screening compound: N-(3-methoxyphenyl)-4-(4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L486-0405
N-(3-methoxyphenyl)-4-(4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L486-0405

Molecular Formula

C21H22N4O3 (C21 H22 N4 O3)

Compound Name

N-(3-methoxyphenyl)-4-(4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide

IUPAC name

N-(3-methoxyphenyl)-4-(4-oxo-34-dihydroquinazolin-3-yl)piperidine-1-carboxamide

SMILES

COc1cccc(NC(N(CC2)CCC2N(C=Nc2c3cccc2)C3=O)=O)c1

InChI

InChI=1S/C21H22N4O3/c1-28-17-6-4-5-15(13-17)23-21(27)24-11-9-16(10-12-24)25-14-22-19-8-3-2-7-18(19)20(25)26/h2-8,13-14,16H,9-12H2,1H3,(H,23,27)

InChI Key

ZLLCQHIGBMOUEH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457093

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.313

Distribution Coefficient, logD

2.313

Water Solubility, LogSw

-3.11

Polar Surface Area

58.547

Acid Dissociation Constant (pKa)

13.05

Base Dissociation Constant (pKb)

2.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L486-0405 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L486-0405 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L486-0405?
Check Price and Availability of L486-0405, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L486-0405 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L486-0405
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L486-0405
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L486-0405 available by request