L486-0581 Screening compound: 4-(7-chloro-4-oxo-3,4-dihydroquinazolin-3-yl)-N-(4-ethylphenyl)piperidine-1-carboxamide

L486-0581 Screening compound: 4-(7-chloro-4-oxo-3,4-dihydroquinazolin-3-yl)-N-(4-ethylphenyl)piperidine-1-carboxamide
L486-0581 Screening compound: 4-(7-chloro-4-oxo-3,4-dihydroquinazolin-3-yl)-N-(4-ethylphenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L486-0581
4-(7-chloro-4-oxo-3,4-dihydroquinazolin-3-yl)-N-(4-ethylphenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L486-0581

Molecular Formula

C22H23ClN4O2 (C22 H23 ClN4 O2)

Compound Name

4-(7-chloro-4-oxo-3,4-dihydroquinazolin-3-yl)-N-(4-ethylphenyl)piperidine-1-carboxamide

IUPAC name

4-(7-chloro-4-oxo-34-dihydroquinazolin-3-yl)-N-(4-ethylphenyl)piperidine-1-carboxamide

SMILES

CCc(cc1)ccc1NC(N(CC1)CCC1N(C=Nc1c2ccc(Cl)c1)C2=O)=O

InChI

InChI=1S/C22H23ClN4O2/c1-2-15-3-6-17(7-4-15)25-22(29)26-11-9-18(10-12-26)27-14-24-20-13-16(23)5-8-19(20)21(27)28/h3-8,13-14,18H,2,9-12H2,1H3,(H,25,29)

InChI Key

IEYIACFXLXSHPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457139

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.944

Distribution Coefficient, logD

3.944

Water Solubility, LogSw

-4.23

Polar Surface Area

51.003

Acid Dissociation Constant (pKa)

13.90

Base Dissociation Constant (pKb)

2.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L486-0581 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L486-0581 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L486-0581?
Check Price and Availability of L486-0581, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L486-0581 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L486-0581
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L486-0581
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L486-0581 available by request