L486-1047 Screening compound: 8-methyl-3-[1-(4-propylbenzenesulfonyl)piperidin-4-yl]-3,4-dihydroquinazolin-4-one

L486-1047 Screening compound: 8-methyl-3-[1-(4-propylbenzenesulfonyl)piperidin-4-yl]-3,4-dihydroquinazolin-4-one
L486-1047 Screening compound: 8-methyl-3-[1-(4-propylbenzenesulfonyl)piperidin-4-yl]-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L486-1047
8-methyl-3-[1-(4-propylbenzenesulfonyl)piperidin-4-yl]-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L486-1047

Molecular Formula

C23H27N3O3S (C23 H27 N3 O3 S)

Compound Name

8-methyl-3-[1-(4-propylbenzenesulfonyl)piperidin-4-yl]-3,4-dihydroquinazolin-4-one

IUPAC name

8-methyl-3-[1-(4-propylbenzenesulfonyl)piperidin-4-yl]-34-dihydroquinazolin-4-one

SMILES

CCCc(cc1)ccc1S(N(CC1)CCC1N(C=Nc1c2cccc1C)C2=O)(=O)=O

InChI

InChI=1S/C23H27N3O3S/c1-3-5-18-8-10-20(11-9-18)30(28,29)25-14-12-19(13-15-25)26-16-24-22-17(2)6-4-7-21(22)23(26)27/h4,6-11,16,19H,3,5,12-15H2,1-2H3

InChI Key

YWJORKZDASTLQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457241

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.264

Distribution Coefficient, logD

4.264

Water Solubility, LogSw

-4.31

Polar Surface Area

54.993

Acid Dissociation Constant (pKa)

26.80

Base Dissociation Constant (pKb)

2.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

L486-1047 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L486-1047 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L486-1047?
Check Price and Availability of L486-1047, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L486-1047 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L486-1047
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L486-1047
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L486-1047 available by request