L487-0196 Screening compound: ethyl 2-[(6-{[(4-ethoxyphenyl)carbamoyl]amino}-2-phenylquinolin-4-yl)oxy]acetate

L487-0196 Screening compound: ethyl 2-[(6-{[(4-ethoxyphenyl)carbamoyl]amino}-2-phenylquinolin-4-yl)oxy]acetate
L487-0196 Screening compound: ethyl 2-[(6-{[(4-ethoxyphenyl)carbamoyl]amino}-2-phenylquinolin-4-yl)oxy]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-0196
ethyl 2-[(6-{[(4-ethoxyphenyl)carbamoyl]amino}-2-phenylquinolin-4-yl)oxy]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-0196

Molecular Formula

C28H27N3O5 (C28 H27 N3 O5)

Compound Name

ethyl 2-[(6-{[(4-ethoxyphenyl)carbamoyl]amino}-2-phenylquinolin-4-yl)oxy]acetate

IUPAC name

ethyl 2-[(6-{[(4-ethoxyphenyl)carbamoyl]amino}-2-phenylquinolin-4-yl)oxy]acetate

SMILES

CCOC(COc1c(cc(cc2)NC(Nc(cc3)ccc3OCC)=O)c2nc(-c2ccccc2)c1)=O

InChI

InChI=1S/C28H27N3O5/c1-3-34-22-13-10-20(11-14-22)29-28(33)30-21-12-15-24-23(16-21)26(36-18-27(32)35-4-2)17-25(31-24)19-8-6-5-7-9-19/h5-17H,3-4,18H2,1-2H3,(H2,29,30,33)

InChI Key

SGGQVAVZZKVDNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128387

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.282

Distribution Coefficient, logD

6.282

Water Solubility, LogSw

-5.58

Polar Surface Area

75.469

Acid Dissociation Constant (pKa)

12.87

Base Dissociation Constant (pKb)

3.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.90

L487-0196 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L487-0196 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-0196?
Check Price and Availability of L487-0196, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L487-0196 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-0196
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-0196
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-0196 available by request