L487-0264 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-[4-methoxy-2-(4-methylphenyl)quinolin-6-yl]urea

L487-0264 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-[4-methoxy-2-(4-methylphenyl)quinolin-6-yl]urea
L487-0264 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-[4-methoxy-2-(4-methylphenyl)quinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-0264
1-(4-bromo-2-fluorophenyl)-3-[4-methoxy-2-(4-methylphenyl)quinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-0264

Molecular Formula

C24H19BrFN3O2 (C24 H19 BrFN3 O2)

Compound Name

1-(4-bromo-2-fluorophenyl)-3-[4-methoxy-2-(4-methylphenyl)quinolin-6-yl]urea

IUPAC name

1-(4-bromo-2-fluorophenyl)-3-[4-methoxy-2-(4-methylphenyl)quinolin-6-yl]urea

SMILES

Cc(cc1)ccc1-c1cc(OC)c(cc(cc2)NC(Nc(ccc(Br)c3)c3F)=O)c2n1

InChI

InChI=1S/C24H19BrFN3O2/c1-14-3-5-15(6-4-14)22-13-23(31-2)18-12-17(8-10-20(18)28-22)27-24(30)29-21-9-7-16(25)11-19(21)26/h3-13H,1-2H3,(H2,27,29,30)

InChI Key

QDVIBACSPYHLBX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457353

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.34

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.266

Distribution Coefficient, logD

7.259

Water Solubility, LogSw

-5.75

Polar Surface Area

47.533

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

5.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

L487-0264 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L487-0264 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-0264?
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What is the minimum amount of L487-0264 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-0264
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-0264
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-0264 available by request