L487-0811 Screening compound: ethyl 2-[(6-{[(3-chlorophenyl)carbamoyl]amino}-2-(4-fluorophenyl)quinolin-4-yl)oxy]acetate

L487-0811 Screening compound: ethyl 2-[(6-{[(3-chlorophenyl)carbamoyl]amino}-2-(4-fluorophenyl)quinolin-4-yl)oxy]acetate
L487-0811 Screening compound: ethyl 2-[(6-{[(3-chlorophenyl)carbamoyl]amino}-2-(4-fluorophenyl)quinolin-4-yl)oxy]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-0811
ethyl 2-[(6-{[(3-chlorophenyl)carbamoyl]amino}-2-(4-fluorophenyl)quinolin-4-yl)oxy]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-0811

Molecular Formula

C26H21ClFN3O4 (C26 H21 ClFN3 O4)

Compound Name

ethyl 2-[(6-{[(3-chlorophenyl)carbamoyl]amino}-2-(4-fluorophenyl)quinolin-4-yl)oxy]acetate

IUPAC name

ethyl 2-[(6-{[(3-chlorophenyl)carbamoyl]amino}-2-(4-fluorophenyl)quinolin-4-yl)oxy]acetate

SMILES

CCOC(COc1c(cc(cc2)NC(Nc3cccc(Cl)c3)=O)c2nc(-c(cc2)ccc2F)c1)=O

InChI

InChI=1S/C26H21ClFN3O4/c1-2-34-25(32)15-35-24-14-23(16-6-8-18(28)9-7-16)31-22-11-10-20(13-21(22)24)30-26(33)29-19-5-3-4-17(27)12-19/h3-14H,2,15H2,1H3,(H2,29,30,33)

InChI Key

MDHCIDYMNFSIEL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457487

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.801

Distribution Coefficient, logD

6.801

Water Solubility, LogSw

-6.43

Polar Surface Area

68.345

Acid Dissociation Constant (pKa)

11.54

Base Dissociation Constant (pKb)

3.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

L487-0811 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L487-0811 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-0811?
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What is the minimum amount of L487-0811 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-0811
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-0811
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-0811 available by request