L487-0839 Screening compound: 3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-cyclohexylurea

L487-0839 Screening compound: 3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-cyclohexylurea
L487-0839 Screening compound: 3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-cyclohexylurea alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-0839
3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-cyclohexylurea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-0839

Molecular Formula

C23H24ClN3O2 (C23 H24 ClN3 O2)

Compound Name

3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-cyclohexylurea

IUPAC name

3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-cyclohexylurea

SMILES

COc(c1c2)cc(-c(cc3)ccc3Cl)nc1ccc2NC(NC1CCCCC1)=O

InChI

InChI=1S/C23H24ClN3O2/c1-29-22-14-21(15-7-9-16(24)10-8-15)27-20-12-11-18(13-19(20)22)26-23(28)25-17-5-3-2-4-6-17/h7-14,17H,2-6H2,1H3,(H2,25,26,28)

InChI Key

JPVYJQQYGHFAMU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.92

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.368

Distribution Coefficient, logD

6.367

Water Solubility, LogSw

-6.36

Polar Surface Area

49.278

Acid Dissociation Constant (pKa)

13.50

Base Dissociation Constant (pKb)

4.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L487-0839 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L487-0839 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-0839?
Check Price and Availability of L487-0839, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L487-0839 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-0839
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-0839
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-0839 available by request