L487-0866 Screening compound: 3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)urea

L487-0866 Screening compound: 3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)urea
L487-0866 Screening compound: 3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-0866
3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-0866

Molecular Formula

C25H20ClN3O4 (C25 H20 ClN3 O4)

Compound Name

3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)urea

IUPAC name

3-[2-(4-chlorophenyl)-4-methoxyquinolin-6-yl]-1-(23-dihydro-14-benzodioxin-6-yl)urea

SMILES

COc(c1c2)cc(-c(cc3)ccc3Cl)nc1ccc2NC(Nc(cc1)cc2c1OCCO2)=O

InChI

InChI=1S/C25H20ClN3O4/c1-31-23-14-21(15-2-4-16(26)5-3-15)29-20-8-6-17(12-19(20)23)27-25(30)28-18-7-9-22-24(13-18)33-11-10-32-22/h2-9,12-14H,10-11H2,1H3,(H2,27,28,30)

InChI Key

DNSGXAWSJVJZQX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457506

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.9

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.728

Distribution Coefficient, logD

5.727

Water Solubility, LogSw

-6.11

Polar Surface Area

64.054

Acid Dissociation Constant (pKa)

12.12

Base Dissociation Constant (pKb)

4.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

L487-0866 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L487-0866 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-0866?
Check Price and Availability of L487-0866, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L487-0866 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-0866
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-0866
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-0866 available by request