L487-1136 Screening compound: methyl 2-{[2-(3-chlorophenyl)-6-{[(2-phenylethyl)carbamoyl]amino}quinolin-4-yl]oxy}acetate

L487-1136 Screening compound: methyl 2-{[2-(3-chlorophenyl)-6-{[(2-phenylethyl)carbamoyl]amino}quinolin-4-yl]oxy}acetate
L487-1136 Screening compound: methyl 2-{[2-(3-chlorophenyl)-6-{[(2-phenylethyl)carbamoyl]amino}quinolin-4-yl]oxy}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-1136
methyl 2-{[2-(3-chlorophenyl)-6-{[(2-phenylethyl)carbamoyl]amino}quinolin-4-yl]oxy}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-1136

Molecular Formula

C27H24ClN3O4 (C27 H24 ClN3 O4)

Compound Name

methyl 2-{[2-(3-chlorophenyl)-6-{[(2-phenylethyl)carbamoyl]amino}quinolin-4-yl]oxy}acetate

IUPAC name

methyl 2-{[2-(3-chlorophenyl)-6-{[(2-phenylethyl)carbamoyl]amino}quinolin-4-yl]oxy}acetate

SMILES

COC(COc(c1c2)cc(-c3cccc(Cl)c3)nc1ccc2NC(NCCc1ccccc1)=O)=O

InChI

InChI=1S/C27H24ClN3O4/c1-34-26(32)17-35-25-16-24(19-8-5-9-20(28)14-19)31-23-11-10-21(15-22(23)25)30-27(33)29-13-12-18-6-3-2-4-7-18/h2-11,14-16H,12-13,17H2,1H3,(H2,29,30,33)

InChI Key

IHFULIJPHMZTRQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.96

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.483

Distribution Coefficient, logD

5.483

Water Solubility, LogSw

-5.91

Polar Surface Area

69.929

Acid Dissociation Constant (pKa)

12.59

Base Dissociation Constant (pKb)

3.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L487-1136 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L487-1136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-1136?
Check Price and Availability of L487-1136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L487-1136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-1136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-1136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-1136 available by request