L487-1604 Screening compound: 1-(3-chlorophenyl)-3-(4-methoxy-2-methylquinolin-6-yl)urea

L487-1604 Screening compound: 1-(3-chlorophenyl)-3-(4-methoxy-2-methylquinolin-6-yl)urea
L487-1604 Screening compound: 1-(3-chlorophenyl)-3-(4-methoxy-2-methylquinolin-6-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-1604
1-(3-chlorophenyl)-3-(4-methoxy-2-methylquinolin-6-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-1604

Molecular Formula

C18H16ClN3O2 (C18 H16 ClN3 O2)

Compound Name

1-(3-chlorophenyl)-3-(4-methoxy-2-methylquinolin-6-yl)urea

IUPAC name

1-(3-chlorophenyl)-3-(4-methoxy-2-methylquinolin-6-yl)urea

SMILES

Cc1cc(OC)c(cc(cc2)NC(Nc3cccc(Cl)c3)=O)c2n1

InChI

InChI=1S/C18H16ClN3O2/c1-11-8-17(24-2)15-10-14(6-7-16(15)20-11)22-18(23)21-13-5-3-4-12(19)9-13/h3-10H,1-2H3,(H2,21,22,23)

InChI Key

WYOITXQXDJTIFI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128439

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.8

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.990

Distribution Coefficient, logD

4.989

Water Solubility, LogSw

-4.98

Polar Surface Area

48.309

Acid Dissociation Constant (pKa)

11.54

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

L487-1604 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L487-1604 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-1604?
Check Price and Availability of L487-1604, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L487-1604 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-1604
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-1604
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-1604 available by request