L487-1630 Screening compound: 3-(4-methoxy-2-methylquinolin-6-yl)-1-[3-(trifluoromethyl)phenyl]urea

L487-1630 Screening compound: 3-(4-methoxy-2-methylquinolin-6-yl)-1-[3-(trifluoromethyl)phenyl]urea
L487-1630 Screening compound: 3-(4-methoxy-2-methylquinolin-6-yl)-1-[3-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L487-1630
3-(4-methoxy-2-methylquinolin-6-yl)-1-[3-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L487-1630

Molecular Formula

C19H16F3N3O2 (C19 H16 F3 N3 O2)

Compound Name

3-(4-methoxy-2-methylquinolin-6-yl)-1-[3-(trifluoromethyl)phenyl]urea

IUPAC name

3-(4-methoxy-2-methylquinolin-6-yl)-1-[3-(trifluoromethyl)phenyl]urea

SMILES

Cc1cc(OC)c(cc(cc2)NC(Nc3cccc(C(F)(F)F)c3)=O)c2n1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.279

Distribution Coefficient, logD

5.279

Water Solubility, LogSw

-5.48

Polar Surface Area

48.309

Acid Dissociation Constant (pKa)

11.01

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

L487-1630 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Ion Channels
  • Phosphatases

References: we are preparing a list of scientific research reports with L487-1630 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L487-1630?
Check Price and Availability of L487-1630, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L487-1630 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L487-1630
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L487-1630
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L487-1630 available by request