L488-0767 Screening compound: 8-chloro-2-[(4-fluorophenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one

L488-0767 Screening compound: 8-chloro-2-[(4-fluorophenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one
L488-0767 Screening compound: 8-chloro-2-[(4-fluorophenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L488-0767
8-chloro-2-[(4-fluorophenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L488-0767

Molecular Formula

C19H16ClFN2O (C19 H16 ClFN2 O)

Compound Name

8-chloro-2-[(4-fluorophenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one

IUPAC name

8-chloro-2-[(4-fluorophenyl)methyl]-1H2H3H4H5H10H-benzo[b]16-naphthyridin-10-one

SMILES

O=C1c(cc(cc2)Cl)c2NC2=C1CN(Cc(cc1)ccc1F)CC2

InChI

InChI=1S/C19H16ClFN2O/c20-13-3-6-17-15(9-13)19(24)16-11-23(8-7-18(16)22-17)10-12-1-4-14(21)5-2-12/h1-6,9H,7-8,10-11H2,(H,22,24)

InChI Key

XRBXGUYEIVKOQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128444

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

342.8

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.129

Distribution Coefficient, logD

3.497

Water Solubility, LogSw

-4.46

Polar Surface Area

27.914

Acid Dissociation Constant (pKa)

6.88

Base Dissociation Constant (pKb)

3.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

L488-0767 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L488-0767 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L488-0767?
Check Price and Availability of L488-0767, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L488-0767 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L488-0767
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L488-0767
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L488-0767 available by request