L488-1831 Screening compound: 8-chloro-2-[(3-methylphenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one

L488-1831 Screening compound: 8-chloro-2-[(3-methylphenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one
L488-1831 Screening compound: 8-chloro-2-[(3-methylphenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L488-1831
8-chloro-2-[(3-methylphenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L488-1831

Molecular Formula

C20H19ClN2O (C20 H19 ClN2 O)

Compound Name

8-chloro-2-[(3-methylphenyl)methyl]-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-10-one

IUPAC name

8-chloro-2-[(3-methylphenyl)methyl]-1H2H3H4H5H10H-benzo[b]16-naphthyridin-10-one

SMILES

Cc1cccc(CN(CC2)CC3=C2Nc(ccc(Cl)c2)c2C3=O)c1

InChI

InChI=1S/C20H19ClN2O/c1-13-3-2-4-14(9-13)11-23-8-7-19-17(12-23)20(24)16-10-15(21)5-6-18(16)22-19/h2-6,9-10H,7-8,11-12H2,1H3,(H,22,24)

InChI Key

XGFABYHRLDGSEH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128454

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.84

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.747

Distribution Coefficient, logD

4.114

Water Solubility, LogSw

-4.68

Polar Surface Area

27.914

Acid Dissociation Constant (pKa)

6.88

Base Dissociation Constant (pKb)

4.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L488-1831 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L488-1831 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L488-1831?
Check Price and Availability of L488-1831, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L488-1831 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L488-1831
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L488-1831
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L488-1831 available by request