L489-1663 Screening compound: 2-{6,9-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2-fluorophenyl)acetamide

L489-1663 Screening compound: 2-{6,9-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2-fluorophenyl)acetamide
L489-1663 Screening compound: 2-{6,9-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-1663
2-{6,9-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-1663

Molecular Formula

C22H22FN3O2 (C22 H22 FN3 O2)

Compound Name

2-{6,9-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2-fluorophenyl)acetamide

IUPAC name

2-{69-dimethyl-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-(2-fluorophenyl)acetamide

SMILES

Cc1ccc(C)c(NC2=C3CN(CC(Nc(cccc4)c4F)=O)CC2)c1C3=O

InChI

InChI=1S/C22H22FN3O2/c1-13-7-8-14(2)21-20(13)22(28)15-11-26(10-9-17(15)25-21)12-19(27)24-18-6-4-3-5-16(18)23/h3-8H,9-12H2,1-2H3,(H,24,27)(H,25,28)

InChI Key

BHJLEPKAIALCPM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457605

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.680

Distribution Coefficient, logD

3.535

Water Solubility, LogSw

-4.01

Polar Surface Area

48.113

Acid Dissociation Constant (pKa)

7.80

Base Dissociation Constant (pKb)

2.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L489-1663 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L489-1663 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-1663?
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What is the minimum amount of L489-1663 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-1663
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-1663
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-1663 available by request