L489-1751 Screening compound: 2-{9-chloro-6-methoxy-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(3-chlorophenyl)methyl]acetamide

L489-1751 Screening compound: 2-{9-chloro-6-methoxy-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(3-chlorophenyl)methyl]acetamide
L489-1751 Screening compound: 2-{9-chloro-6-methoxy-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(3-chlorophenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-1751
2-{9-chloro-6-methoxy-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(3-chlorophenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-1751

Molecular Formula

C22H21Cl2N3O3 (C22 H21 Cl2 N3 O3)

Compound Name

2-{9-chloro-6-methoxy-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(3-chlorophenyl)methyl]acetamide

IUPAC name

2-{9-chloro-6-methoxy-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-[(3-chlorophenyl)methyl]acetamide

SMILES

COc(ccc(Cl)c12)c2NC(CCN(CC(NCc2cc(Cl)ccc2)=O)C2)=C2C1=O

InChI

InChI=1S/C22H21Cl2N3O3/c1-30-18-6-5-16(24)20-21(18)26-17-7-8-27(11-15(17)22(20)29)12-19(28)25-10-13-3-2-4-14(23)9-13/h2-6,9H,7-8,10-12H2,1H3,(H,25,28)(H,26,29)

InChI Key

DGTDSFMYQWNBFS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457629

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.33

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.667

Distribution Coefficient, logD

1.617

Water Solubility, LogSw

-4.34

Polar Surface Area

57.764

Acid Dissociation Constant (pKa)

5.35

Base Dissociation Constant (pKb)

1.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L489-1751 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with L489-1751 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-1751?
Check Price and Availability of L489-1751, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L489-1751 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-1751
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-1751
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-1751 available by request