L489-1909 Screening compound: N-(4-chloro-3-fluorophenyl)-2-{9-fluoro-6-methyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}acetamide

L489-1909 Screening compound: N-(4-chloro-3-fluorophenyl)-2-{9-fluoro-6-methyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}acetamide
L489-1909 Screening compound: N-(4-chloro-3-fluorophenyl)-2-{9-fluoro-6-methyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-1909
N-(4-chloro-3-fluorophenyl)-2-{9-fluoro-6-methyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-1909

Molecular Formula

C21H18ClF2N3O2 (C21 H18 ClF2 N3 O2)

Compound Name

N-(4-chloro-3-fluorophenyl)-2-{9-fluoro-6-methyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}acetamide

IUPAC name

N-(4-chloro-3-fluorophenyl)-2-{9-fluoro-6-methyl-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}acetamide

SMILES

Cc(c(NC1=C2CN(CC(Nc(cc3)cc(F)c3Cl)=O)CC1)c1C2=O)ccc1F

InChI

InChI=1S/C21H18ClF2N3O2/c1-11-2-5-15(23)19-20(11)26-17-6-7-27(9-13(17)21(19)29)10-18(28)25-12-3-4-14(22)16(24)8-12/h2-5,8H,6-7,9-10H2,1H3,(H,25,28)(H,26,29)

InChI Key

CZWUOARBKRPLEL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457675

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.307

Distribution Coefficient, logD

3.410

Water Solubility, LogSw

-4.73

Polar Surface Area

48.811

Acid Dissociation Constant (pKa)

6.56

Base Dissociation Constant (pKb)

1.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L489-1909 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L489-1909 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-1909?
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What is the minimum amount of L489-1909 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-1909
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-1909
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-1909 available by request