L489-1920 Screening compound: 2-{6,7-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

L489-1920 Screening compound: 2-{6,7-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide
L489-1920 Screening compound: 2-{6,7-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-1920
2-{6,7-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-1920

Molecular Formula

C23H24FN3O2 (C23 H24 FN3 O2)

Compound Name

2-{6,7-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

IUPAC name

2-{67-dimethyl-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

SMILES

Cc(cc1)c(C)c(NC2=C3CN(CC(NCc(cc4)ccc4F)=O)CC2)c1C3=O

InChI

InChI=1S/C23H24FN3O2/c1-14-3-8-18-22(15(14)2)26-20-9-10-27(12-19(20)23(18)29)13-21(28)25-11-16-4-6-17(24)7-5-16/h3-8H,9-13H2,1-2H3,(H,25,28)(H,26,29)

InChI Key

VLGYEMMFYSBLEW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457684

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.687

Distribution Coefficient, logD

3.662

Water Solubility, LogSw

-3.87

Polar Surface Area

50.133

Acid Dissociation Constant (pKa)

8.62

Base Dissociation Constant (pKb)

2.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L489-1920 in Drug Discovery

Included in Screening Libraries

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L489-1920 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-1920?
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What is the minimum amount of L489-1920 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-1920
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-1920
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-1920 available by request