L489-1978 Screening compound: 2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

L489-1978 Screening compound: 2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide
L489-1978 Screening compound: 2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-1978
2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-1978

Molecular Formula

C23H24FN3O2 (C23 H24 FN3 O2)

Compound Name

2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

IUPAC name

2-{68-dimethyl-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-[(4-fluorophenyl)methyl]acetamide

SMILES

Cc(cc1C)cc2c1NC(CCN(CC(NCc(cc1)ccc1F)=O)C1)=C1C2=O

InChI

InChI=1S/C23H24FN3O2/c1-14-9-15(2)22-18(10-14)23(29)19-12-27(8-7-20(19)26-22)13-21(28)25-11-16-3-5-17(24)6-4-16/h3-6,9-10H,7-8,11-13H2,1-2H3,(H,25,28)(H,26,29)

InChI Key

IFFCJBPIUJAZBE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457731

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.424

Distribution Coefficient, logD

3.375

Water Solubility, LogSw

-3.58

Polar Surface Area

50.133

Acid Dissociation Constant (pKa)

8.32

Base Dissociation Constant (pKb)

2.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L489-1978 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L489-1978 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-1978?
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What is the minimum amount of L489-1978 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-1978
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-1978
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-1978 available by request