L489-2002 Screening compound: 2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(4-fluorophenyl)acetamide

L489-2002 Screening compound: 2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(4-fluorophenyl)acetamide
L489-2002 Screening compound: 2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(4-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-2002
2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(4-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-2002

Molecular Formula

C22H22FN3O2 (C22 H22 FN3 O2)

Compound Name

2-{6,8-dimethyl-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(4-fluorophenyl)acetamide

IUPAC name

2-{68-dimethyl-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-(4-fluorophenyl)acetamide

SMILES

Cc(cc1C)cc2c1NC(CCN(CC(Nc(cc1)ccc1F)=O)C1)=C1C2=O

InChI

InChI=1S/C22H22FN3O2/c1-13-9-14(2)21-17(10-13)22(28)18-11-26(8-7-19(18)25-21)12-20(27)24-16-5-3-15(23)4-6-16/h3-6,9-10H,7-8,11-12H2,1-2H3,(H,24,27)(H,25,28)

InChI Key

PKDFTSZQZIKQNU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457743

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.846

Distribution Coefficient, logD

3.797

Water Solubility, LogSw

-3.90

Polar Surface Area

48.811

Acid Dissociation Constant (pKa)

8.32

Base Dissociation Constant (pKb)

1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

References: we are preparing a list of scientific research reports with L489-2002 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-2002?
Check Price and Availability of L489-2002, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L489-2002 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-2002
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-2002
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-2002 available by request